Zepbound has transformed weight management for many adults. This tirzepatide-based injection helps with obesity and related conditions. Its popularity surged in recent years.
High costs often deter potential users. List prices hover around $1,000 monthly without aid. Savings programs aim to ease this burden.
In 2025, options include manufacturer discounts and pharmacy coupons. Understanding these helps budget effectively.
What Makes Zepbound Costly
The base price reflects research and production. Eli Lilly sets the wholesale acquisition cost high.
Insurance varies widely by plan. Some cover it for specific diagnoses. Self-pay routes offer alternatives. Direct programs from Lilly provide transparency.
Zepbound Costs in 2025: The Direct Answer
Zepbound’s list price is about $1,086 per month for pens in 2025. Without insurance, expect $1,000+ at pharmacies.
With commercial insurance and savings card, it drops to $25 per fill if covered. Uncovered commercial plans qualify for up to $469 off, around $650 monthly.
Self-pay vials via LillyDirect start at $299 for lowest dose, up to $449 for higher ones. This direct option bypasses insurance hurdles.
Factors Influencing Monthly Price
Dose strength impacts vial costs. Lower doses like 2.5mg cost $299, higher like 15mg $449.
Refill timing matters. Buy within 45 days for discounted rates. Location and pharmacy affect retail prices. Urban areas may charge more.
Savings Card Eligibility and Use
Commercial insurance required. No government plans like Medicare or Medicaid.
Activate online or via doctor. Maximum savings $150 monthly, $1,950 yearly. Expires December 31, 2025. Renew or check updates annually.
Direct Purchase Through LillyDirect
Vials available for cash pay. No insurance needed.
Prices: $299 (2.5mg), $399 (5mg), $449 (higher doses) per month supply.
Auto-applies discounts on timely refills. Convenient home delivery.
| Cost Option | Without Insurance | With Savings Card (Covered Insurance) | With Savings Card (Uncovered Insurance) | Notes |
|---|---|---|---|---|
| List Price (Pens) | $1,086/month | $25/month (up to 3 months) | ~$650/month (up to $469 off) | Commercial insurance only; expires 12/31/2025 |
| LillyDirect Vials | $299-$449/month | N/A | N/A | Dose-dependent; refills within 45 days for discount |
| GoodRx Coupon | ~$995/month | N/A | N/A | 22% off retail; varies by pharmacy |
| Without Any Aid | $1,000-$1,300/month | N/A | N/A | Pharmacy retail price; no discounts applied |
This table compares key pricing paths. Vials offer best self-pay value.
Insurance Coverage Details
Many commercial plans cover Zepbound for obesity or OSA. Prior authorization often required. Medicare excludes weight loss drugs in 2025. Possible for OSA in limited cases.
Medicaid varies by state. Some like California cover without PA. Appeals succeed over 65% with documentation. Doctors submit medical necessity letters.
Additional Discount Options
Third-party sites like GoodRx lower to $995. SingleCare around $950. Not as good as manufacturer card. Use when ineligible for Lilly’s program.
Patient assistance rare for Zepbound. Lilly Cares excludes it currently.
Tips to Lower Your Costs
Shop pharmacies for best prices. Costco or Walmart may offer deals. Combine with lifestyle programs. Some insurers bundle coverage.
Monitor announcements. Potential Medicare changes in 2026.
- Check eligibility online for savings card.
- Use LillyDirect for vials if uninsured.
- Appeal denials with doctor support.
- Compare coupons before filling.
Future Pricing Outlook
Prices may stabilize or drop slightly. Competition from generics later. Government deals aim for affordability. Watch for 2026 expansions. Individual plans evolve yearly. Renew coverage discussions annually.
Summary
Zepbound costs start high at $1,086 list but savings make it accessible. Savings card offers $25 with coverage.
Self-pay vials from $299 provide reliable option. Insurance appeals and coupons add flexibility.
Plan ahead for eligibility. Consistent use maximizes health benefits.
FAQ
What is the list price of Zepbound in 2025?
Zepbound’s list price is $1,086 per month for pre-filled pens. This applies regardless of dose. Actual costs drop significantly with savings.
How can I get Zepbound for $25 a month?
Use the savings card with commercial insurance that covers it. Pay as low as $25 per fill. Must activate and meet terms; expires end of 2025.
What does Zepbound cost without insurance?
Without aid, expect $1,000-$1,300 monthly at pharmacies. LillyDirect vials reduce to $299-$449 depending on dose. Refill promptly for best rates.
Does Medicare cover Zepbound in 2025?
Generally no for weight loss. Limited possible for OSA. Check plan specifics; appeals or self-pay as alternatives. Changes may come in 2026.
Dr. Hamza is a medical content reviewer with over 12+ years of experience in healthcare research and patient education. He specializes in evidence-based health information, medications, and chronic conditions. His reviews are grounded in trusted medical sources and current clinical guidelines to ensure accuracy, transparency, and reliability. Content reviewed by Dr. Hamza is intended for educational purposes and is not a substitute for professional medical advice.